Patrick C.N. Rensen is professor Metabolic Aspects of Vascular Disease at Leiden University Medical Center, Leiden, The Netherlands, and guest professor at Xi’an Jiaotong University, Xi’an, China. He is Established Investigator of the Dutch Heart Foundation, past chairman of the European Lipoprotein Club (ELC), current board member of the Dutch Atherosclerosis Society (DAS) and Scandinavian Society for Atherosclerosis Research (SSAR), and ambassador of the city of Leiden. His research focuses on modulation of energy metabolism, via lifestyle and pharmacological approaches, as a strategy to prevent and treat obesity and associated diseases including type 2 diabetes, metabolic dysfunction-associated steatotic liver disease and atherosclerotic cardiovascular disease. To this end, his group combines mechanistic experiments in a unique humanized mouse model for cardiometabolic diseases (i.e., APOE*3-Leiden.CETP mice) with human intervention studies in metabolically compromised individuals. Current grant support includes the Dutch Research Council (NWO), Dutch Heart Foundation (DHF), Dutch Diabetes Research Foundation (DFN), European Federation for the Study of Diabetes (EFSD), Leiden University Fund (LUF), Dutch Cardiovascular Alliance (DCVA) and the Chinese Scholarship Council (CSC). His research resulted in patent applications and >390 publications in peer-reviewed scientific journals  (>13,500 citations; H-index 62).