Hester den Ruijter is a Professor of Cardiovascular disease in women at the University Medical Center in Utrecht. Her team works on the diagnosis of heart disease in women. Most available diagnostics for heart disease have been tested in men and directly rranslated to women. Nowadays we are increasingly becoming aware that male-derived tests do not always detect heart disease in women. There are interesting sex differences in the pathophysiology of heart disease that may explain why diagnostic tests developed in men fail to detect heart disease in women. Therefore, her group focusses on novel biomarkers and methodologies that facilitate the diagnosis of heart disease in women, and to understand why these sex differences occur.