Guido Zaman
Managing Director & Founder, Oncolines
Guido Zaman is the Managing Director and founder of Oncolines B.V., a Symeres company specializing in precision medicine services in oncology and cancer immunotherapy. Oncolines supports clinical and preclinical biopharma companies, as well as academic institutions worldwide, in differentiating their drugs and drug candidates through advanced cancer cell line profiling, mechanism-of-action studies, bioinformatics and biochemical assays.
Previously, Guido was also co-founder of Netherlands Translational Research Center (NTRC), a biotech company established in Oss in 2011 by former employees of Organon/MSD. He holds a Ph.D. in Science from Radboud University Nijmegen and conducted post-doctoral research for five years at the Netherlands Cancer Institute in Amsterdam, focusing on drug transporters in the laboratory of Prof. Piet Borst
Before becoming a biotech entrepreneur, Guido held various project and line management roles at Organon/MSD, where he contributed to drug discovery programs targeting protein kinases, G protein-coupled receptors and nuclear hormone receptors in the Immunology and Women’s Health therapeutic areas.
Guido is a named inventor on seven granted patents and has co-authored over 90 publications in peer-reviewed scientific journals.
Presentation: Target identification via comparative cancer cell panel profiling
I will introduce Oncolines B.V., a company based at the Pivot Park in Oss, named after its proprietary Oncolines® human cancer cell line panel and profiling services. Through cancer cell panel profiling, Oncolines identifies predictive drug response biomarkers, uncovers new disease indications, and discovers synergistic drug combinations. During the Day One presentation at Drug Medicines Days, I will present a case study demonstrating how comparative cancer cell panel profiling, integrated with bioinformatics and biochemical assays, can uncover previously unknown drug targets and reveal novel therapeutic applications for existing drugs.
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