Structural Biology in Pharmacology and Signaling

17 October 2024 | 10:00 - 11:15

This parallel session will focus on applications of structural biophysics to investigate drug interactions and signaling responses through specific structural interactions. High resolution structural biology has provided unparalleled insight into the specific interactions underlying pharmacological targeting and intervention. These results allow for the accurate screening and design of drugs against experimentally determined binding interfaces as well as determining key coupling interactions for signaling. The aim of this session is to highlight structural biological methods as they apply to pharmaceutical and biological research underway in the Netherlands.

Chair: Chris Schafer (VU)

Speakers: Joost Uitdehaag (Crossfire Oncology), Chris Schafer (VU)

Selected Abstract Presenters: Shuang Shi (VU Amsterdam), Daan van der Es (LACDR)

FIGON Partners: AIMMS, KNCV=MCCB, HollandBIO

Session Schedule

10:00 - 10:25Chris Schafer (VU): Atypical structure and regulation of an atypical chemokine receptor
10:25 - 10:50
Dr. Joost Uitdehaag (Crossfire Oncology)
10:50 - 11:00Selected Abstract Presentation by Shuang Shi: Structural basis of ligand recognition and design of antihistamines targeting histamine H4 receptor
11:00 - 11:10
Selected Abstract Presentation by Daan van der Es: Chemical biology approaches in a medicinal chemistry context: Probing the adenosine receptors

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